SERIC LEVELS OF C-REACTIVE PROTEIN AND MYELOPEROXIDASE AND PARAMETERS OF GLYCEMIC CONTROL IN DIABETICS TYPE 2

Abstract

The objective of the study was to evaluate the serum levels of C-reactive protein (CRP) and myeloperoxidase (MPO) and glycemic control parameters in patients with type 2 diabetes mellitus (T2DM). This was a comparative study conducted with 86 individuals of both sexes, aged 20 to 59 years with a 1:1 ratio between control and T2DM. Body weight, body mass index, waist circumference, fasting glucose, insulinemia, glycated hemoglobin percentage, homeostasis model assessment insulin resistance (HOMA-IR), ultrasensitive CRP and MPO were evaluated. Regarding glycemic control, 55.8% and 86.1% of diabetics had glycated hemoglobin and fasting glucose above 7% and 130 mg / dL, respectively. CRP and MPO values were significantly higher (p <0.05) in the diabetic group, where 51.2% had CRP above 3 mg / L. There was no statistically significant association (p <0.05) between glycemic control parameters and CRP concentrations. A high proportion of diabetics presented inadequate glycemic control and high concentrations of ultra-sensitive CRP, although no relationship was found between glycemic control parameters and CRP.