EVALUATION OF THE “IN VITRO” ANTIMICROBIAL ACTIVITY OF PLANT EXTRACTS FROM BRYOPHYTES AGAINST MICROORGANISMS OF CLINICAL IMPORTANCE

Abstract

Especially in recent decades, numerous efforts have been directed towards giving
plants their real role and value in antimicrobial therapy. In this study, the activity
antibacterial treatment of crude ethanolic extract of Octoblepharum albidum, Groutiella tomentosa,
Marchesinia brachiata in vitro against strains of Escherichia coli, Klebsiella pneumoniae,
Pseudomonas aeruginosa and Staphylococcus aureus. For the botanical species studied,
it was also proposed: to investigate potential bioactive constituents; identify the
Minimum Inhibitory Concentration (MIC), by the broth microdilution method with plates
of 96 wells and demonstrate the bactericidal and/or bacteriostatic activity of the extracts. You
results of the phytochemical analysis of G. tomentosa identified the presence of triterpeniodes
free pentacyclics and saponins, for O. albidum showed the presence of steroids and alkaloids
and for M. brachiata the presence of condensed tannins and steroids was found. It can be
conclude that the crude ethanolic extracts of G. tomentosa and M. brachiata had an effect
bactericidal for the K. pneumoniae strain at a concentration of 4,000 μg/mL, while
for O. albidum, there was no bactericidal activity against the strains used in the study.
Considering this, the results found, significant for the continuity
investigative.