OVERLOAD FROM AN ELITE BASKETBALL GAME REDUCED CARDIOMETABOLIC RISK AND INCREASED OXIDATIVE STRESS WITHOUT CAUSING KIDNEY STRESS

Abstract

The aim of this study was to assess the impact of an elite official basketball game from a Brazilian championship on redox, metabolic, and renal biomarkers. The sample comprised 10 elite male players who underwent anthropometric and ergoespirometric evaluations weeks before the match, hydration analysis, and Subjective Perception of Effort (PSE) immediately before and after the game. Additionally, Heart Rate (HR), energy expenditure, Oxygen Consumption (VO2), and other hemodynamic variables were assessed during the game. Urine and blood samples were collected before, immediately after, and 24 hours post-game. Data were analyzed using one-way repeated measures ANOVA followed by Bonferroni's post hoc test, while Pearson's correlation coefficient was used to measure linear correlations between quantitative variables. Statistical significance was set at 5%. Results indicated lower levels of Serum Creatinine, increased levels of 8-isoprostane and TBARS, as well as lower Castelli I and II atherogenic indices; however, there were no isolated changes in metabolic, antioxidant defense (SOD, GPx, catalase, and thiol), and renal (nGAL and nephrin) biomarkers. The effects of an official basketball game improved the cardiometabolic risk of athletes without altering enzymatic antioxidant activity or causing renal stress. Additionally, the increase in lipid peroxidation observed post-game raises hypotheses regarding adaptive exercise mechanisms and the overload of antioxidant pathways.