EARLY DETECTION OF PHYSIOLOGICAL PHENOMENA IN POTENTIAL ORGAN DONORS IN CRITICAL CARE: AN INTEGRATIVE REVIEW

Authors

  • Larissa Gabrielly da Silva Morais Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO) https://orcid.org/0000-0002-8591-5546
  • Letícia Emilly da Silva Morais Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO) https://orcid.org/0000-0002-7113-5899
  • Dayane Pessoa de Araújo Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO) https://orcid.org/0000-0002-2366-4024

DOI:

https://doi.org/10.16891/2317-434X.v13.e5.a2025.id2330

Keywords:

Brain Death, Physiology, Intensive Care Units, Organ Transplantation

Abstract

This study aimed to analyze the main physiological changes in brain death and how their early recognition by a multidisciplinary team influences organ donation. Additionally, it sought to describe relevant findings in the literature on this central topic. This study employs an integrative literature review as its methodological design. The interrelationships identified during the review of the nine studies allowed for the identification of thematic categories and subcategories, revealing the central phenomenon of this research. Therefore, the findings suggest that early identification of key physiological changes indicative of brain death, combined with team training in antibiotic therapy, assertive and early use of vasoactive drugs, and blood pressure control in an intensive care unit with advanced care capabilities, further enhances the organ transplant process.

Author Biographies

Larissa Gabrielly da Silva Morais, Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO)

Possess a Bachelor's degree from the University of the State of Rio Grande do Norte (UERN/FAEN). Specialist in the General Intensive Care Unit and the Neonatal and Pediatric Intensive Care Unit of the Faculdade Venda Nova do Imigrante (FAVENI). Master's degree in Physiological Sciences from the University of the State of Rio Grande do Norte in the Multicentre Postgraduate Program in Physiological Sciences (UERN/PPGMCF) with a line of research in Neurophysiology and behavior. Bolsista da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES). Currently, she works in research focused on the areas of neuropharmacology and teaching of physiological sciences.

Letícia Emilly da Silva Morais, Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO)

Possessed a Bachelor's Degree in Nursing from the University of the State of Rio Grande do Norte (UERN/FAEN). Specialist in women's health, pediatrician and neonatology at the Faculdade Venda New do Imigrante (FAVENI), Master in Physiological Sciences at the University of the State of Rio Grande do Norte in the Multicentre Postgraduate Program in Physiological Sciences (UERN/PPGMCF). Currently, she works on research focused on the areas of Comparative Animal Physiology.

Dayane Pessoa de Araújo, Universidade do Estado do Rio Grande do Norte (UERN), Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas (PPGMCF), Laboratório de Neurologia Experimental (LABNEURO)

Postgraduate in Nursing at the University of Fortelaza (UNIFOR). Specialist in Clinical Care at the State University of Ceará (UECE). Master and Doctor in Pharmacology (Neuropharmacology) by the Department of Physiology and Pharmacology of the Federal University of Ceará (UFC). Currently she is Associate Professor V of the Nursing Department of the University of the State of Rio Grande do Norte and Professor of the Multicentre Postgraduate Program in Physiological Sciences of SBFis. She has research experience in Neurophysiology and Neuropharmacology, focusing mainly on the following topics: Neuroinflammation, Oxidative stress, Natural products, Antioxidants.

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Published

2025-07-11

How to Cite

da Silva Morais, L. G., da Silva Morais, L. E., & Pessoa de Araújo, D. (2025). EARLY DETECTION OF PHYSIOLOGICAL PHENOMENA IN POTENTIAL ORGAN DONORS IN CRITICAL CARE: AN INTEGRATIVE REVIEW. Revista Interfaces: Saúde, Humanas E Tecnologia, 13(1), 5429–5439. https://doi.org/10.16891/2317-434X.v13.e5.a2025.id2330

Issue

Vol. 13 No. 1 (2025):

Section

Artigos