ATIVIDADE ANTIOXIDANTE DE ÓLEOS ESSENCIAS DA FAMÍLIA MYRTACEAE PELO MÉTODO DE DPPH: UMA REVISÃO DE LITERATURA
DOI:
https://doi.org/10.16891/701Resumo
O estresse oxidativo corresponde a um desequilíbrio entre agentes oxidantes e antioxidantes, que levam ao predomínio de espécies reativas de oxigênio e como resultante podem provocar danos celulares e contribuir para o desenvolvimento de doenças e envelhecimento. Os óleos essenciais (OEs) constitui-se de uma mistura de compostos voláteis extraídos de plantas aromáticas que tem sido correlacionado ao efeito antioxidante. O presente estudo consiste numa revisão de literatura sobre a atividade antioxidante de OEs de espécies da família Myrtaceae avaliados pelo método de DPPH e os componentes majoritários correlacionados a inibição oxidante. Foram selecionados 16 artigos de acordo com os critérios de inclusão nas plataformas de banco de dados Pubmed, Sciene Sirect e Google Scholar. Os OEs da família Myrtaceae apresentaram potencial antioxidante e o método de DPPH demonstrou-se promissor na avaliação do efeito antioxidante de OEs. Os componentes majoritários mais prevalentes entre as espécies abordadas foram os monoterpenos. O estudo de compostos bioativos com princípios antioxidantes são de grande importância para a desenvolvimento de tratamentos e prevenção ao estresse oxidativo.
Referências
Adnan Mohan (2019). Bioactive potential of essential oil extracted from the leaves of Eucalyptus globulus (Myrtaceae). Journal of Pharmacognosy and Phytochemistry, 8(1), 213-216.
Amaral et al. (2018). Essential oil yield and composition of native species of the Myrtaceae family from “Campos Gerais” of the Atlantic Forest in Parana State. Ciência e Natura, 40, e1. DOI:10.5902/2179460X27337
Asif, Mohammad (2015). Chemistry and antioxidant activity of plants containing some phenolic compounds. Chemistry international, 1(1), 35-52.
Ashour, M., Wink, M., & Gershenzon, J. (2018). Biochemistry of terpenoids: monoterpenes, sesquiterpenes and diterpenes. Annual Plant Reviews online, 258-303. DOI: doi.org/10.1002/9781119312994.apr0427
Asit Ray et al. (2019). Chemical composition and antioxidant activities of essential oil of Hedychium greenii and Hedychium gracile from India. Natural product research, 33(10), 1482-1485. DOI: 10.1080/14786419.2017.1416384
Azizkhani, M., & Puramin, S. (2019). Antioxidant Potential of Eugenia caryophyllus, Satureja hortensis and Artemisia dracunculus Essential Oils in Grape Seed Oil. Iranian Journal of Veterinary Medicine, 13(2), 217-227. DOI:10.22059/ijvm.2019.266294.1004927
Badawy, M. E., Marei, G. I. K., Rabea, E. I., & Taktak, N. E. (2019). Antimicrobial and antioxidant activities of hydrocarbon and oxygenated monoterpenes against some foodborne pathogens through in vitro and in silico studies. Pesticide Biochemistry and Physiology. DOI: 10.1016/j.pestbp.2019.05.008
Benny, A., & Thomas, J. (2019). Essential Oils as Treatment Strategy for Alzheimer ? s Disease: Current and Future Perspectives Authors. DOI:10.1055/a-0758-0188
Bida, M. R., Dominguez, J., Jones Miguel, D., Guerrero, A., & Pagano, T. (2019). Essential oil compounds from the leaf of Eugenia samanensis Alain (Myrtaceae), a species endemic to the Samaná Peninsula, Dominican Republic. Journal of Essential Oil Research, 31(2), 154-159. DOI: 10.1080/10412905.2018.1518275
Bouyahya et al. (2017). In vitro screening of antibacterial and antioxidant activities of essential oils from four Moroccan medicinal plants. Microbiology Research Journal International, 4, 5.
Bouzabata et al. (2016). The Genus Myrtus L. in Algeria: composition and biological aspects of essential oils from M. communis and M. nivellei: a review. Chemistry & biodiversity, 13(6), 672-680.
Bugarin et al. (2014). Essential oil of Eucalyptus gunnii Hook. as a novel source of antioxidant, antimutagenic and antibacterial agents. Molecules, 19(11), 19007-19020. DOI: 10.3390/molecules191119007
Carneiro et al. (2017). Chemical composition, antioxidant and antibacterial activities of essential oils from leaves and flowers of Eugenia klotzschiana Berg (Myrtaceae). Anais da Academia Brasileira de Ciências, 89(3), 1907-1915. DOI: 10.1590/0001-3765201720160652
Couto et al. (2019). Essential oils of basil chemotypes: Major compounds, binary mixtures, and antioxidant activity. DOI:10.1016/j.foodchem.2019.04.078
Cutillas, A. B., Carrasco, A., Martinez-Gutierrez, R., Tomas, V., & Tudela, J. (2018). Thymus mastichina L. essential oils from Murcia (Spain): Composition and antioxidant, antienzymatic and antimicrobial bioactivities. PloS one, 13(1), e0190790. DOI: 10.1371/journal.pone.0190790
Dhami et al. ?-Pinene Rich Bark Essential Oils of Zanthoxylum armatum DC. from Three Different Altitudes of Uttarakhand, India and their Antioxidant, in vitro Anti-inflammatory and Antibacterial Activity. Journal of Essential Oil Bearing Plants, 22(3), 660-674.
Dias et al. (2019). Chemical composition and in vitro antibacterial and antiproliferative activities of the essential oil from the leaves of Psidium myrtoides O. Berg (Myrtaceae). Natural product research, 33(17), 2566-2570. DOI: 10.1080/14786419.2018.1457664
Donado-Pestana et al. (2018). Polyphenols from Brazilian native Myrtaceae fruits and their potential health benefits against obesity and its associated complications. Current opinion in food science, 19, 42-49. DOI: 10.1016/j.cofs.2018.01.001
Farag et al. (2018). Characterization of essential oils from Myrtaceae species using ATR-IR vibrational spectroscopy coupled to chemometrics. Industrial crops and products, 124, 870-877. DOI: 10.1016/j.indcrop.2018.07.066
Figueiredo, A. C., Barroso, J. G., & Pedro, L. G. (2007). Plantas Aromáticas e Medicinais. Factores que afectam a produção. Potencialidades e aplicações das plantas aromáticas e medicinais. Curso Teórico-Prático, 3, 1-18.
F
igueiredo et al. (2019). Composition, antioxidant capacity and cytotoxic activity of Eugenia uniflora L. chemotype-oils from the Amazon. Journal of ethnopharmacology, 232, 30-38. DOI: 10.1016/j.jep.2018.12.011
Filippin, L. I., Vercelino, R., Marroni, N. A. P., & Xavier, R. M. (2008). Influência de processos redox na resposta inflamatória da artrite reumatóide. Revista brasileira de reumatologia. Campinas. Vol. 48, n. 1 (jan. 2008), p. 17-24.
Finkel, T., & Holbrook, N. J. (2000). Oxidants, oxidative stress and the biology of ageing. nature, 408(6809), 239.
Gad, H. A., Ayoub, I. M., & Wink, M. (2019). Phytochemical profiling and seasonal variation of essential oils of three Callistemon species cultivated in Egypt. PloS one, 14(7), e0219571. DOI: 10.1371/journal.pone.0219571
Gevú et al. (2019). Chemical Composition and Anti-Candida and Anti-Trypanosoma cruzi Activities of Essential Oils from the Rhizomes and Leaves of Brazilian Species of Renealmia L. fil. Records of natural products, 13(3), 268-280. DOI: 10.25135/rnp.105.18.08.125
Gonzalez-Burgos, E., & Gomez-Serranillos, M. P. (2012). Terpene compounds in nature: a review of their potential antioxidant activity. Current medicinal chemistry, 19(31), 5319-5341.
Granato et al. (2018). Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods?. Food chemistry, 264, 471-475. DOI: 10.1016/j.foodchem.2018.04.012
Hafsa et al. (2016). Physical, antioxidant and antimicrobial properties of chitosan films containing Eucalyptus globulus essential oil. LWT-Food Science and Technology, 68, 356-364. DOI: 10.1016/j.lwt.2015.12.050
Hsouna et al. (2019). Chemical composition and hepatoprotective effect of essential oil from Myrtus communis L. flowers against CCL 4-induced acute hepatotoxicity in rats. RSC advances, 9(7), 3777-3787. DOI:10.1039/c8ra08204a
Jawed, H., Shamim, M., Sohail, S., Firdous, U., & Iqbal Khan, N. (2019). Antioxidative activity of clove (syzygium aromaticum) oil administration in Middle cerebral artery occlusion (mcao) Models of acute focal cerebral ischemia. Pakistan Journal of Neurological Sciences (PJNS), 14(1), 10-15.
Kim, G. H., Kim, J. E., Rhie, S. J., & Yoon, S. (2015). The role of oxidative stress in neurodegenerative diseases. Experimental neurobiology, 24(4), 325-340. DOI: 10.5607/en.2015.24.4.325
Kurti et al. (2019). Chemical composition, antioxidant and antimicrobial activities of essential oils of different Pinus species from Kosovo. Journal of Essential Oil Research, 31(4), 263-275. DOI: 10.1080/10412905.2019.1584591
Larayetan, R. A., Okoh, O. O., Sadimenko, A., & Okoh, A. I. (2017). Terpene constituents of the aerial parts, phenolic content, antibacterial potential, free radical scavenging and antioxidant activity of Callistemon citrinus (Curtis) Skeels (Myrtaceae) from Eastern Cape Province of South Africa. BMC complementary and alternative medicine, 17(1), 292. DOI 10.1186/s12906-017-1804-2
Maggio et al. (2019). Comparative chemical composition and bioactivity of leaves essential oils from nine Sicilian accessions of Myrtus communis L. Journal of Essential Oil Research, 1-10. DOI: 10.1080/10412905.2019.1610089
Musthafa, K. S., Sianglum, W., Saising, J., Lethongkam, S., & Voravuthikunchai, S. P. (2017). Evaluation of phytochemicals from medicinal plants of Myrtaceae family on virulence factor production by Pseudomonas aeruginosa. Apmis, 125(5), 482-490. DOI: 10.1111/apm.12672
Nascimento et al. (2018). Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol. Journal of ethnopharmacology, 210, 351-358. DOI: 10.1016/j.jep.2017.08.030
Obiloma et al. (2019). Terpene-Rich Medicinal Plant Spices for Flavoring of Processed Tropical Food. American Journal of Plant Sciences, 10(04), 572. DOI: doi.org/10.4236/ajps.2019.104041
Okoh, S. O., Okoh, O. O., & Okoh, A. I. (2019). Seasonal variation of volatile oil composition and antioxidant property of aerial parts of Syzygium paniculatum Gaertn. grown in the Eastern Cape, South Africa. Natural product research, 33(15), 2276-2280. DOI:10.1080/14786419.2018.1497032
Oliveira et al. (2019). Antioxidant and antifungal activities of the flowers’ essential oil of Tagetes minuta,(Z)-tagetone and thiotagetone. Journal of Essential Oil Research, 31(2), 160-169. DOI: 10.1080/10412905.2018.1519465
Radünz et al. (2019). Antimicrobial and antioxidant activity of unencapsulated and encapsulated clove (Syzygium aromaticum, L.) essential oil. Food chemistry, 276, 180-186. DOI:10.1016/j.foodchem.2018.09.173
Rahal et al. (2014). Oxidative stress, prooxidants, and antioxidants: the interplay. BioMed research international, 2014. DOI:10.1155/2014/761264
Ray et al. (2019). Chemical composition and antioxidant activities of essential oil of Hedychium greenii and Hedychium gracile from India. Natural product research, 33(10), 1482-1485. DOI: 0.1080/14786419.2017.1416384
Rinnerthaler, M., Bischof, J., Streubel, M., Trost, A., & Richter, K. (2015). Oxidative stress in aging human skin. Biomolecules, 5(2), 545-589. DOI: 10.3390/biom5020545
Salem et al. (2018). Bioactivity of essential oils extracted from Cupressus macrocarpa branchlets and Corymbia citriodora leaves grown in Egypt. BMC complementary and alternative medicine, 18(1), 23. DOI 10.1186/s12906-018-2085-0
Salmazzo et al. (2019). Chemical composition and antiproliferative, antioxidant and trypanocidal activities of the fruits from Campomanesia xanthocarpa (Mart.) O. Berg (Myrtaceae). Natural product research, 1-5. DOI: 10.1080/14786419.2019.1607333
Sánchez-Valle, V., & Méndez-Sánchez, N. (2018). Estrés oxidativo, antioxidantes y enfermedad. Médica Sur, 20(3), 161-168.
Scur et al. (2016). Antimicrobial and antioxidant activity of essential oil and different plant extracts of Psidium cattleianum Sabine. Brazilian Journal of Biology, 76(1), 101-108. DOI: 10.1590/1519-6984.13714
Siddique, S., Parveen, Z., & Mazhar, S. (2017). Chemical composition, antibacterial and antioxidant activities of essential oils from leaves of three Melaleuca species of Pakistani flora. Arabian Journal of Chemistry. DOI: 0.1016/j.arabjc.2017.01.018
Siddique, S., Mazhar, S., & Parveen, Z. (2018). Chemical characterization, antioxidant and antimicrobial activities of essential oil from Melaleuca quinquenervia leaves.
Sies, Helmunt (2015). Oxidative stress: a concept in redox biology and medicine. Redox biology, 4, 180-183. DOI: 10.1016/j.redox.2015.01.002
Silva, M. L. C., Costa, R. S., dos Santos Santana, A., & Koblitz, M. G. B. (2010). Compostos fenólicos, carotenóides e atividade antioxidante em produtos vegetais. Semina: Ciências Agrárias, 31(3), 669-681.
Silva et al. (2017). Chemical composition of four essential oils of Eugenia from the Brazilian Amazon and their cytotoxic and antioxidant activity. Medicines, 4(3), 51. DOI: 10.3390/medicines4030051
Silva et al. (2018). Chemical composition and antibacterial activity of Cymbopogon citratus and Cymbopogon flexuosus essential oils. Ciência e Natura, 40, 2. DOI: DOI:10.5902/2179460X27569
Singh et al. (2012). Assessment of in vitro antioxidant activity of essential oil of Eucalyptus citriodora (lemon-scented Eucalypt; Myrtaceae) and its major constituents. LWT-Food science and Technology, 48(2), 237-241. DOI:10.1016/j.lwt.2012.03.019
Smeriglio et al. (2019). Feijoa Fruit Peel: Micro-morphological Features, Evaluation of Phytochemical Profile, and Biological Properties of Its Essential Oil. Antioxidants, 8(8), 320. DOI: 10.3390/antiox8080320
Sontakke, M. D., Syed, H. M., Salve, R. V., & Shinde, E. M. (2019). Studies on antioxidant activity and characterization of essential oil extracted from Cinnamomum zeylanicum Bark.
Sviech et al. (2019). Biological activity of essential oil of pitanga (Eugenia uniflora L.) LEAVES. Boletim do Centro de Pesquisa de Processamento de Alimentos, 36(1).
Takao, L. K., Imatomi, M., & Gualtieri, S. C. J. (2015). Antioxidant activity and phenolic content of leaf infusions of Myrtaceae species from Cerrado (Brazilian Savanna). Brazilian Journal of Biology, 75(4), 948-952. DOI: 10.1590/1519-6984.03314
Talón, E., Vargas, M., Chiralt, A., & González-Martínez, C. (2019). Antioxidant starch-based films with encapsulated eugenol. Application to sunflower oil preservation. LWT, 108290. DOI:10.1016/j.lwt.2019.108290
Tietbohl et al. (2019). Green insecticide against Chagas disease: effects of essential oil from Myrciaria floribunda (Myrtaceae) on the development of Rhodnius prolixus nymphs. Journal of Essential Oil Research, 1-11. DOI: 10.1080/10412905.2019.1631894
Tolba, H., Moghrani, H., Aboun, A., & Maachi, R. (2018). Essential oil of Algerian Eucalyptus citriodora: Chemical composition, antioxidant and antimicrobial activities. Nature & Technology, (18), 19-27.
Vasconcelos et al. (2007). Espécies reativas de oxigênio e de nitrogênio, antioxidantes e marcadores de dano oxidativo em sangue humano: principais métodos analíticos para sua determinação. Química nova.
Veras et al. (2019). Algrizea Minor Sobral, Faria & Proença (Myrteae, Myrtaceae): chemical composition, antinociceptive, antimicrobial and antioxidant activity of essential oil. Natural product research, 1-5. DOI: 10.1080/14786419.2019.1602832
Wu, S. B., Long, C., & Kennelly, E. J. (2013). Phytochemistry and health benefits of jaboticaba, an emerging fruit crop from Brazil. Food Research International, 54(1), 148-159. DOI:10.1016/j.foodres.2013.06.021
